URL details: joelostblom.com/publication/zandstra-tewary-2019/
URL title:
High-Throughput Micropatterning Platform Reveals Nodal-Dependent Bisection of Peri-Gastrulation–Associated versus Preneurulation
URL description:
In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human pluripotent stem cell (hPSC) lines for their ability to undergo peri-gastrulation–like fate patterning upon bone morphogenetic protein 4 (BMP4) treatment of geometrically confined colonies and observed significant heterogeneity in their differentiation propensit
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